added references, and finished citing intro paragrpah

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2026-05-11 20:26:48 -05:00
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3 changed files with 66 additions and 72 deletions

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%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
%% This is a "template" model document for submission to the
%% American Chemical Society (ACS).
%%
%% The guidance here contains information about how you may wish to
%% modify it to match the requirements of various ACS journals. The
%% ACS do *not* typeset accepted articles using LaTeX, so there is
%% no specific class required.
%%
%% This template deliberately does *not* seek to reproduce
%% the layout of the typeset journal: this is explicitly not
%% required by the ACS for LaTeX submissions.
%%
%% Please report any issues with the template at
%% https://github.com/josephwright/acs-template/issues
%%
%% Released under the Creative Commons 0 license
%% https://creativecommons.org/public-domain/cc0/
%%
%% Copyight (c) 2025 Joseph Wright
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
\documentclass[letterpaper]{article}
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%% Font setup - delete if you are using LuaLaTeX
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\usepackage[T1]{fontenc}
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%% Adjust the margins and allow for line spacing
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\usepackage{geometry}
\geometry{margin = 1in}
\usepackage{setspace}
\usepackage{chemfig}
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%% Reference support
%%
%% The recommended method for producing the reference section is
%% to use biblatex. If you wish to use a classical BibTeX
%% approach, this is easiest to achieve using the achemso package.
%% In that case, you should remove the biblatex lines.
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
% You can adjust the printing of DOI, article title, etc. using
% package options, e.g. "doi = true"; see the biblatex manual for
% details of adjusting the number of authors printed, e.g.
% "maxnames = 15" to print no more than 15 authors.
\usepackage[style = chem-acs]{biblatex}
\addbibresource{acs-template.bib}
% If you are using classical BibTeX, remove the above lines and
% uncomment:
%\usepackage{achemso}
\addbibresource{references.bib}
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%% Graphic inclusion and scheme and chart support
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\usepackage{graphicx}
\usepackage{float}
\newfloat{scheme}{htbp}{los}
@@ -63,30 +19,16 @@
\floatname{chart}{Chart}
\newfloat{graph}{htbp}{loh}
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
%% Common support packages
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\usepackage{chemformula} % Formulas using \ch{}
% or
\usepackage[version = 4]{mhchem} % Formulas using \ce{}
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%% Many journals require that sections are unnumbered: this
%% is activated here
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\setcounter{secnumdepth}{-1}
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%% Place any additional macros here. Please use \newcommand* where
%% possible, and avoid layout-changing macros (which are not used
%% when typesetting).
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\newcommand*\mycommand[1]{\texttt{\emph{#1}}}
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%% Author and title data:
%% the authblk package is currently the simplest way to provide this
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
\usepackage{authblk}
\author[1]{Shivam Tripathi}
\author[1]{Keshav Anand}
@@ -112,7 +54,7 @@ from Commerical Asprin Tablets to Form Methyl Salicylate}
\section{Introduction}
Acetylsalicylic acid (ASA), \ch{C9H8O4}, is a synthetic organic derivative of salicylic acid
and is commonly known as aspirin.\\
and is commonly known as aspirin~\cite{Fijakowski2022}.\\
\begin{figure}[ht]
\centering
\vspace{1em} % Adds space above the molecule
@@ -123,15 +65,15 @@ and is commonly known as aspirin.\\
\end{figure}
Commercial aspirin is commonly synthesized from salicylic acid through Eq~\ref{eq:aspirin-syn},
and the two molecules differ by an ester group (\ch{-OCOCH3}).
and the two molecules differ by an ester group (\ch{-OCOCH3})~\cite{Sneader2000}.
\begin{equation}
\ce{C7H6O3 + C4H6O3 ->[H2SO4] C9H8O4 + CH3COOH}
\label{eq:aspirin-syn}
\end{equation} \\
Another common derivative product of salicylic acid is methyl salicylate, \ch{C8H8O3}, commonly referred to
as wintergreen oil. Methyl salicylate is commonly used in edibles (e.g. gum, mints), perfumes, and pain-relief
ointments (e.g. Icy Hot, BenGay). Methyl salicylate also differs with salicylic acid by a single ester group and
has simply been esterified differently than ASA. \\
ointments (e.g. Icy Hot, BenGay)~\cite{Guo2022}. Methyl salicylate also differs with salicylic acid by a single ester group and
has simply been esterified differently than ASA.\\
\begin{figure}[ht]
\centering
@@ -142,7 +84,7 @@ has simply been esterified differently than ASA. \\
\label{fig:methyl-salicylate}
\end{figure}
Due to the similarity between the two molecules, ASA can be reacted to synthesize methyl salicylate.
Due to the similarity between the two molecules, ASA can be reacted to synthesize methyl salicylate~\cite{Hartel2009}.
The purpose of this experiment was to convert acetylsalicylic acid obtained from
commercial aspirin tablets into methyl salicylate through acid-catalyzed esterification
in methanol under reflux conditions.
@@ -276,12 +218,7 @@ The following files are available free of charge.
\item Filename-2: brief description
\end{itemize}
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
%% If you are using classical BibTeX rather than biblatex,
%% remove the \printbibliography and uncomment the \bibliograpy one
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\printbibliography
%\bibliography{acs-template.bib}
\newpage

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references.bib Normal file
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@@ -0,0 +1,57 @@
@article{Fijakowski2022,
title = {Acetylsalicylic AcidPrimus Inter Pares in Pharmacology},
volume = {27},
ISSN = {1420-3049},
url = {http://dx.doi.org/10.3390/molecules27238412},
DOI = {10.3390/molecules27238412},
number = {23},
journal = {Molecules},
publisher = {MDPI AG},
author = {Fijałkowski, Łukasz and Skubiszewska, Magdalena and Grześk, Grzegorz and Koech, Frankline Kiptoo and Nowaczyk, Alicja},
year = {2022},
month = Dec,
pages = {8412}
}
@article{Sneader2000,
title = {The discovery of aspirin: a reappraisal},
volume = {321},
ISSN = {1468-5833},
url = {http://dx.doi.org/10.1136/bmj.321.7276.1591},
DOI = {10.1136/bmj.321.7276.1591},
number = {7276},
journal = {BMJ},
publisher = {BMJ},
author = {Sneader, W.},
year = {2000},
month = Dec,
pages = {15911594}
}
@article{Guo2022,
title = {Safety and efficacy of compound methyl salicylate liniment for topical pain: A multicenter real-world study in China},
volume = {13},
ISSN = {1663-9812},
url = {http://dx.doi.org/10.3389/fphar.2022.1015941},
DOI = {10.3389/fphar.2022.1015941},
journal = {Frontiers in Pharmacology},
publisher = {Frontiers Media SA},
author = {Guo, Jie and Hu, Xiaolei and Wang, Jing and Yu, Bin and Li, Juan and Chen, Jianting and Nie, Xiaoli and Zheng, Zhijian and Wang, Shixuan and Qin, Qun},
year = {2022},
month = Oct
}
@article{Hartel2009,
title = {Preparation of Oil of Wintergreen from Commercial Aspirin Tablets. A Microscale Experiment Highlighting Acyl Substitutions},
volume = {86},
ISSN = {1938-1328},
url = {http://dx.doi.org/10.1021/ed086p475},
DOI = {10.1021/ed086p475},
number = {4},
journal = {Journal of Chemical Education},
publisher = {American Chemical Society (ACS)},
author = {Hartel, Aaron M. and Hanna, James M.},
year = {2009},
month = Apr,
pages = {475}
}