added references, and finished citing intro paragrpah
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79
main.tex
79
main.tex
@@ -1,61 +1,17 @@
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%% This is a "template" model document for submission to the
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%% American Chemical Society (ACS).
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%%
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%% The guidance here contains information about how you may wish to
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%% modify it to match the requirements of various ACS journals. The
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%% ACS do *not* typeset accepted articles using LaTeX, so there is
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%% no specific class required.
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%%
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%% This template deliberately does *not* seek to reproduce
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%% the layout of the typeset journal: this is explicitly not
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%% required by the ACS for LaTeX submissions.
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%%
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%% Please report any issues with the template at
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%% https://github.com/josephwright/acs-template/issues
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%%
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%% Released under the Creative Commons 0 license
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%% https://creativecommons.org/public-domain/cc0/
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%%
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%% Copyight (c) 2025 Joseph Wright
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\documentclass[letterpaper]{article}
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%% Font setup - delete if you are using LuaLaTeX
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\usepackage[T1]{fontenc}
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\usepackage{geometry}
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\geometry{margin = 1in}
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\usepackage{setspace}
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\usepackage{chemfig}
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%% Reference support
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%%
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%% The recommended method for producing the reference section is
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%% to use biblatex. If you wish to use a classical BibTeX
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%% approach, this is easiest to achieve using the achemso package.
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%% In that case, you should remove the biblatex lines.
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% You can adjust the printing of DOI, article title, etc. using
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% package options, e.g. "doi = true"; see the biblatex manual for
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% details of adjusting the number of authors printed, e.g.
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% "maxnames = 15" to print no more than 15 authors.
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\usepackage[style = chem-acs]{biblatex}
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\addbibresource{acs-template.bib}
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% If you are using classical BibTeX, remove the above lines and
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% uncomment:
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%\usepackage{achemso}
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\addbibresource{references.bib}
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%% Graphic inclusion and scheme and chart support
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\usepackage{graphicx}
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\usepackage{float}
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\newfloat{scheme}{htbp}{los}
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@@ -63,30 +19,16 @@
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\floatname{chart}{Chart}
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\newfloat{graph}{htbp}{loh}
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%% Common support packages
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\usepackage{chemformula} % Formulas using \ch{}
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% or
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\usepackage[version = 4]{mhchem} % Formulas using \ce{}
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%% Many journals require that sections are unnumbered: this
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%% is activated here
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\setcounter{secnumdepth}{-1}
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%% Place any additional macros here. Please use \newcommand* where
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%% possible, and avoid layout-changing macros (which are not used
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%% when typesetting).
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\newcommand*\mycommand[1]{\texttt{\emph{#1}}}
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%% Author and title data:
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%% the authblk package is currently the simplest way to provide this
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\usepackage{authblk}
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\author[1]{Shivam Tripathi}
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\author[1]{Keshav Anand}
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@@ -112,7 +54,7 @@ from Commerical Asprin Tablets to Form Methyl Salicylate}
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\section{Introduction}
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Acetylsalicylic acid (ASA), \ch{C9H8O4}, is a synthetic organic derivative of salicylic acid
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and is commonly known as aspirin.\\
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and is commonly known as aspirin~\cite{Fijakowski2022}.\\
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\begin{figure}[ht]
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\centering
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\vspace{1em} % Adds space above the molecule
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@@ -123,14 +65,14 @@ and is commonly known as aspirin.\\
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\end{figure}
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Commercial aspirin is commonly synthesized from salicylic acid through Eq~\ref{eq:aspirin-syn},
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and the two molecules differ by an ester group (\ch{-OCOCH3}).
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and the two molecules differ by an ester group (\ch{-OCOCH3})~\cite{Sneader2000}.
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\begin{equation}
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\ce{C7H6O3 + C4H6O3 ->[H2SO4] C9H8O4 + CH3COOH}
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\label{eq:aspirin-syn}
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\end{equation} \\
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Another common derivative product of salicylic acid is methyl salicylate, \ch{C8H8O3}, commonly referred to
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as wintergreen oil. Methyl salicylate is commonly used in edibles (e.g. gum, mints), perfumes, and pain-relief
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ointments (e.g. Icy Hot, BenGay). Methyl salicylate also differs with salicylic acid by a single ester group and
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ointments (e.g. Icy Hot, BenGay)~\cite{Guo2022}. Methyl salicylate also differs with salicylic acid by a single ester group and
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has simply been esterified differently than ASA.\\
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\begin{figure}[ht]
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@@ -142,7 +84,7 @@ has simply been esterified differently than ASA. \\
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\label{fig:methyl-salicylate}
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\end{figure}
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Due to the similarity between the two molecules, ASA can be reacted to synthesize methyl salicylate.
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Due to the similarity between the two molecules, ASA can be reacted to synthesize methyl salicylate~\cite{Hartel2009}.
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The purpose of this experiment was to convert acetylsalicylic acid obtained from
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commercial aspirin tablets into methyl salicylate through acid-catalyzed esterification
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in methanol under reflux conditions.
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@@ -276,12 +218,7 @@ The following files are available free of charge.
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\item Filename-2: brief description
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\end{itemize}
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%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
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%% If you are using classical BibTeX rather than biblatex,
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%% remove the \printbibliography and uncomment the \bibliograpy one
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%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
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\printbibliography
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%\bibliography{acs-template.bib}
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\newpage
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57
references.bib
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57
references.bib
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@@ -0,0 +1,57 @@
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@article{Fijakowski2022,
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title = {Acetylsalicylic Acid–Primus Inter Pares in Pharmacology},
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volume = {27},
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ISSN = {1420-3049},
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url = {http://dx.doi.org/10.3390/molecules27238412},
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DOI = {10.3390/molecules27238412},
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number = {23},
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journal = {Molecules},
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publisher = {MDPI AG},
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author = {Fijałkowski, Łukasz and Skubiszewska, Magdalena and Grześk, Grzegorz and Koech, Frankline Kiptoo and Nowaczyk, Alicja},
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year = {2022},
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month = Dec,
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pages = {8412}
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}
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@article{Sneader2000,
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title = {The discovery of aspirin: a reappraisal},
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volume = {321},
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ISSN = {1468-5833},
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url = {http://dx.doi.org/10.1136/bmj.321.7276.1591},
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DOI = {10.1136/bmj.321.7276.1591},
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number = {7276},
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journal = {BMJ},
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publisher = {BMJ},
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author = {Sneader, W.},
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year = {2000},
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month = Dec,
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pages = {1591–1594}
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}
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@article{Guo2022,
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title = {Safety and efficacy of compound methyl salicylate liniment for topical pain: A multicenter real-world study in China},
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volume = {13},
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ISSN = {1663-9812},
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url = {http://dx.doi.org/10.3389/fphar.2022.1015941},
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DOI = {10.3389/fphar.2022.1015941},
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journal = {Frontiers in Pharmacology},
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publisher = {Frontiers Media SA},
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author = {Guo, Jie and Hu, Xiaolei and Wang, Jing and Yu, Bin and Li, Juan and Chen, Jianting and Nie, Xiaoli and Zheng, Zhijian and Wang, Shixuan and Qin, Qun},
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year = {2022},
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month = Oct
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}
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@article{Hartel2009,
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title = {Preparation of Oil of Wintergreen from Commercial Aspirin Tablets. A Microscale Experiment Highlighting Acyl Substitutions},
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volume = {86},
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ISSN = {1938-1328},
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url = {http://dx.doi.org/10.1021/ed086p475},
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DOI = {10.1021/ed086p475},
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number = {4},
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journal = {Journal of Chemical Education},
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publisher = {American Chemical Society (ACS)},
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author = {Hartel, Aaron M. and Hanna, James M.},
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year = {2009},
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month = Apr,
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pages = {475}
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}
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